LIT-001

CAT: 0804-HY-124733A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-124733A-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM) . LIT-001 improves social interaction in a mouse model of autism[1].
CAS Number
[2245072-21-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Oxytocin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lit-001.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@H](C(N(C)C)=S)CCC1)NCC2=CC=C(C(N3C4=CC=CC=C4NC(N(C)N=C5)=C5C3)=O)C=C2C.O=C(O)C(F)(F)F
Molecular Formula
C30H34F3N7O4S
Molecular Weight
645.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Frantz MC, et al. LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism. J Med Chem. 2018 Oct 11;61 (19) :8670-8692.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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