(R) -VX-11e

• Description :

  (R) -VX-11e (Compound 1) is an ERK2 inhibitor[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ERK

• Type :

  Reference compound

• Related Pathways :

  MAPK/ERK Pathway; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/r-vx-11e.html

• Purity :

  98.73

• Solubility :

  DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=CC(C2=NC(NC3=C(Cl)C=C(F)C=C3)=NC=C2C)=CN1)N[C@@H](CO)C4=CC=CC(Cl)=C4

• Molecular Formula :

  C24H20Cl2FN5O2

• Molecular Weight :

  500.35

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Vanderpool D, et al. Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors. Anal Biochem. 2015 Mar 15;473:46-52.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1680187-43-2]