VX-150

CAT: 0804-HY-139346-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-139346-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VX-150 is an orally active, highly selective NaV1.8 inhibitor. VX-150 has the potential for various pain indications research[1].
CAS Number
[1793080-72-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vx-150.html
Purity
98.36
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1COP(O)(O)=O
Molecular Formula
C21H17F4N2O7P
Molecular Weight
516.34
Precautions
H302, H315, H319
References & Citations
[1]Hemme J Hijma, et al. A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults. Pain Med. 2021 Aug 6;22 (8) :1814-1826.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Nav1.8

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