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Chlorination and Oxidation detection Kit

CAT: 0436-MPOHOCL100-3Size: 500 + 300 TestsDry Ice: NoHazardous: No
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CAT#:0436-MPOHOCL100-3Size:500 + 300 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Can monitor multiple time points to follow kinetics., One-step, no wash assay., Adaptable for High Throughput format., Highly Sensitive.
Label
ICT
Type
Metabolic Assays
Detection Method
Fluorescence plate reader
Assay Protocol
https://cdn.shopify.com/s/files/1/0512/5793/4009/files/MPOHOCL_Protocol_2.pdf?v=1693431067
Components
Part# 4007: Detection Reagent, 1 Vial ('-20C), Part# 3002: 10X Assay Buffer, 60mL (2-8C), Part# 3012: Hydrogen Peroxide, 1000µL of a Stabilized 3% Solution (2-8C), Part# 6015: Myeloperoxidase, 1 Vial at 30Units/mL (2-8C), Part# 4011: APF, 1 Vial (2-8C)
Shipping Conditions
Ships overnight (domestic), International Priority Shipping
Storage Temperature
2-8°C
Target Description
Fluoro MPOHOCL uses a chlorination activity protocol that utilizes a non-fluorescent detection reagent,, APF, which is converted to its fluorescent analog in the presence of HOCl. The kit is used for detection of, MPO chlorination activity in neutrophils and macrophages, as Well as detection of PMN infiltration in tissue, samples (inflammation and innate host defense mechanisms). MPO chlorination activ- ity been implicated, in acute and chronic manifestations of cardiovascular disease and acute and chronic inflammatory, disorders due to chlorination tissue damage.