CCT031374 (hydrobromide)

• Description :

  CCT 031374 hydrobromid is a potent inhibitor of β-catenin/transcription factor (TCF) complex signaling. CCT031374 inhibits TCF-dependent transcription of genes of Wnt signaling pathway. CCT 031374 has antitumor activity[1].

• UNSPSC :

  12352005

• Target :

  Wnt; β-catenin

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cct031374-hydrobromide.html

• Purity :

  98.08

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=C(C2=CC=CC=C2)C=C1)CN3C4=NCCN4C5=CC=CC=C35.[H]Br

• Molecular Formula :

  C23H20BrN3O

• Molecular Weight :

  434.33

• References & Citations :

  [1]Ewan K, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 Jul 15;70 (14) :5963-73.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1219184-91-4]