CCT031374 (hydrobromide)

• UNSPSC Description:

  CCT 031374 hydrobromid is a potent inhibitor of β-catenin/transcription factor (TCF) complex signaling. CCT031374 inhibits TCF-dependent transcription of genes of Wnt signaling pathway. CCT 031374 has antitumor activity[1].

• Target Antigen:

  β-catenin

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cct031374-hydrobromide.html

• Purity:

  98.08

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC=C(C2=CC=CC=C2)C=C1)CN3C4=NCCN4C5=CC=CC=C35.[H]Br

• Molecular Weight:

  434.33

• References & Citations:

  [1]Ewan K, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 Jul 15;70(14):5963-73.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  1219184-91-4