C-7280948

• Description :

  C-7280948 is a selective and potent protein methyltransferase1 (PRMT1) inhibitor with an IC50 value of 12.75 μM[1].

• CAS Number :

  [587850-67-7]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/C-7280948.html

• Purity :

  99.91

• Solubility :

  DMSO : ≥ 38 mg/mL

• Smiles :

  O=S(C1=CC=C(N)C=C1)(NCCC2=CC=CC=C2)=O

• Molecular Formula :

  C14H16N2O2S

• Molecular Weight :

  276.35

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011 Jun 15;19 (12) :3717-3731.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PRMT1