Biotinylated Cynomolgus latent GDF-8 Protein, Avitag™, His Tag

• Background:

  Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.

• Description:

  Biotinylated Cynomolgus latent GDF-8 Protein, Avitag, His Tag (GD8-C82Q3) is expressed from human 293 cells (HEK293) . It contains AA Gly 19 - Ser 375 (Accession # Q95J86) .

• Specifications:

  This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 44.1 kDa. The protein migrates as 11-12 kDa, 40-43 kDa and 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  Q95J86

• Expression Region:

  Gly 19 - Ser 375

• Host:

  HEK293

• Target:

  GDF-8

• Conjugation:

  Biotin-labeled

• Tag:

  N-Avi & N-10xHis

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  90%

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  44.1 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  200ug*1

• Species:

  Cynomolgus