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GSK329

CAT: 0804-HY-117243-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117243-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK329 is a potent and selective diarylurea inhibitor of the cardiac-specific kinase TNNI3K. GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury[1].
CAS Number
1268490-12-5
Product Name Alternative
CXD101
UNSPSC
12352005
Target
MAP3K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gsk329.html
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(Cl)=C(C(Cl)=C1)OC2=NC=NC(NC)=C2)NC3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C19H14Cl2F3N5O2
Molecular Weight
472.25
References & Citations
[1]Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64 (21) :15651-15670.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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