PPM1F Polyclonal Antibody

CAT: 0866-RD88180A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88180A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.
Description
This is a PPM1F Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PPM1F, CAMKP, CaMKPase, FEM-2, POPX2, hFEM-2
Gene ID
9647
Swiss Prot
P49593
Reactivity
Human
Immunogen
Recombinant fusion protein of human PPM1F
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110kDa/113kDa/117kDa
Observed Molecular Weight
118kDa
Host or Source
Rabbit
Isotype
IgG

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