PPM1M Polyclonal Antibody

CAT: 0866-RD219190A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD219190A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX) . PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42) .
Description
This is a PPM1M Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FLJ32332, PP2C eta, PP2C-eta, PP2CE, PP2Ceta, PPM1M, PPM1M, protein phosphatase 1M (PP2C domain containing), Protein phosphatase 1M, Protein phosphatase 2C isoform eta
Swiss Prot
Q96MI6
Accession Number
BC009644
Reactivity
Human, Mouse
Immunogen
Fusion protein of human PPM1M
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.74 mg/mL
Dilution
IHC 1:100-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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