HLA-E Polyclonal Antibody

• Background :

  HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

• Description :

  This is a HLA-E Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HLA-6.2, QA1, HLA-E, EA1.2, EA2.1

• Gene ID :

  3133

• Swiss Prot :

  P13747

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human HLA-E

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  40kDa

• Observed Molecular Weight :

  40kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG