HLA-E Polyclonal Antibody

• Background:

  HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

• Description:

  This is a HLA-E Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HLA-6.2, QA1, HLA-E, EA1.2, EA2.1

• Gene ID:

  3133

• Swiss Prot:

  P13747

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human HLA-E

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  40kDa

• Observed Molecular Weight:

  40kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG