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Recombinant YTHDF1 Monoclonal Antibody

CAT: 0866-RD86990A-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0866-RD86990A-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A) -containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.
Description
This is a Recombinant YTHDF1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
C20orf21, DF1
Gene ID
54915
Swiss Prot
P59326
Reactivity
Human, Hamster
Immunogen
Recombinant protein of human YTHDF1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
77kDa
Observed Molecular Weight
77kDa
Host or Source
Rabbit
Isotype
IgG

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