STAT2 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a STAT2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  STAT2, IMD44, ISGF-3, P113, STAT113

• Gene ID:

  6773

• Swiss Prot:

  P52630

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human STAT2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48-71kDa

• Observed Molecular Weight:

  71kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG