STAT2 Polyclonal Antibody

CAT: 0866-RD90139A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90139A-01Size:60 μL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a STAT2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
STAT2, IMD44, ISGF-3, P113, STAT113
Gene ID
6773
Swiss Prot
P52630
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human STAT2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48-71kDa
Observed Molecular Weight
71kDa
Host or Source
Rabbit
Isotype
IgG

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