STAT4 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

• Description:

  This is a STAT4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  STAT4, SLEB11

• Gene ID:

  6775

• Swiss Prot:

  Q14765

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human STAT4 (NP_003142.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  85 kDa

• Observed Molecular Weight:

  76 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG