SEMA4A Polyclonal Antibody

CAT: 0866-RD88771A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88771A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF) -mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a SEMA4A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SEMA4A, CORD10, RP35, SEMAB, SEMB
Gene ID
64218
Swiss Prot
Q9H3S1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SEMA4A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
20kDa/36kDa/48kDa
Observed Molecular Weight
48kDa
Host or Source
Rabbit
Isotype
IgG

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