SEMA4D Polyclonal Antibody

• Background :

  Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro) . Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

• Description :

  This is a SEMA4D Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, MSEMA, SEM4D, Sema 4d, SEMA J, Semacl2, SemaH, SEMAJ, A8, BB18, GR3

• Swiss Prot :

  Q92854

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Human SEMA4D protein expressed by Mammalian

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal antibody

• Applications :

  WB

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol pH 7.4

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  15kDa

• Observed Molecular Weight :

  15kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG