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SEMA4D Polyclonal Antibody

CAT: 0866-RD90735A-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0866-RD90735A-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro) . Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Description
This is a SEMA4D Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, MSEMA, SEM4D, Sema 4d, SEMA J, Semacl2, SemaH, SEMAJ, A8, BB18, GR3
Swiss Prot
Q92854
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human SEMA4D protein expressed by Mammalian
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal antibody
Applications
WB
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa
Observed Molecular Weight
15kDa
Host or Source
Rabbit
Isotype
IgG

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