CASR Polyclonal Antibody

CAT: 0866-RD87818A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87818A-01Size:60 μL
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Background
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH) -producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Description
This is a CASR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CASR, CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1, hCasR
Gene ID
846
Swiss Prot
P41180
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CASR
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
13kDa/20kDa/109kDa/113kDa
Observed Molecular Weight
113kDa
Host or Source
Rabbit
Isotype
IgG

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