(KD Validated) eIF4E Polyclonal Antibody

• Background:

  The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.

• Description:

  This is a (KD Validated) eIF4E Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E, EIF4E

• Gene ID:

  1977

• Swiss Prot:

  P06730

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human eIF4E

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IF 1:50-1:200, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58kDa/59kDa/60kDa

• Observed Molecular Weight:

  65KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG