(KO Validated) EIF4E Polyclonal Antibody

• Background :

  The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.

• Abbreviation :

  EIF4E

• UniProt :

  P06730

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  A synthetic peptide of human EIF4E (NP_001959.1) .

• Target :

  AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E; EIF4E

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC; IF

• Field of Research :

  Cancer; Epigenetics and Nuclear Signaling

• Purification :

  Affinity purification

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:50-1:100; IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG