ZN-A-1041
CAT:
804-HY-163428-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZN-A-1041
- CAS Number: 2414056-31-6
- UNSPSC Description: ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation[1].
- Target Antigen: EGFR
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/zn-a-1041.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=C(C2=C(N=CN=C2NC3=CC(C)=C(C=C3)OC4=CC5=NC=NN5C=N4)C=C1)O[C@@H]6CCN(CC6(F)F)C
- Molecular Weight: 548.54
- References & Citations: [1]Zhou Ding, et al. uinazoline derivatives as antitumor agents. Patent. N112654612A
- Shipping Conditions: Room temperature
- Clinical Information: Phase 1