Anti-Phosphotyrosine (clone PY20)

• Background:

  Phosphorylationof specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function.

• Host:

  Mouse

• Reactivity:

  Phosphotyrosine- not species dependent

• Not reactive in:

  No confirmed exceptions from predicted reactivity are currently known

• Immunogen:

  balbC mice immunized with phosphotyrosine coupled to carrier protein

• Clonality:

  Monoclonal

• Applications:

  ELISA (ELISA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western blot (WB)

• Dilution:

  To be determined by end user

• Purity:

  Immunogen affinity purified serum in PBS pH 7.4.

• Format:

  Liquid

• Storage Conditions:

  Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

• CAS Number:

  9007-83-4