Products for Research Use Only

SAV1 Polyclonal Antibody

CAT: 0866-RD85448A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD85448A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Description
This is a SAV1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SAV1, SAV, WW45, WWP4
Gene ID
60485
Swiss Prot
Q9H4B6
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SAV1 (NP_068590.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:4000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa
Observed Molecular Weight
45 kDa
Host or Source
Rabbit
Isotype
IgG