ERCC8 Polyclonal Antibody

• Background:

  This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) . CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a ERCC8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ERCC8, CKN1, CSA, UVSS2

• Gene ID:

  1161

• Swiss Prot:

  Q13216

• Reactivity:

  Mouse

• Immunogen:

  A synthetic peptide of human ERCC8 (NP_000073.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  23 kDa/44 kDa

• Observed Molecular Weight:

  44 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG