ERCC8 Polyclonal Antibody

• Background :

  This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) . CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a ERCC8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ERCC8, CKN1, CSA, UVSS2

• Gene ID :

  1161

• Swiss Prot :

  Q13216

• Reactivity :

  Mouse

• Immunogen :

  A synthetic peptide of human ERCC8 (NP_000073.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  23 kDa/44 kDa

• Observed Molecular Weight :

  44 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG