ERCC2 Polyclonal Antibody

• Background :

  The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a ERCC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD

• Gene ID :

  2068

• Swiss Prot :

  P18074

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein of human ERCC2 (NP_001124339.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IF 1:50-1:100

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG