ERCC2 Polyclonal Antibody

• Background:

  The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a ERCC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD

• Gene ID:

  2068

• Swiss Prot:

  P18074

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human ERCC2 (NP_001124339.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  46 kDa/86 kDa

• Observed Molecular Weight:

  80 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG