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MMP8 Polyclonal Antibody

CAT: 0866-RD78577A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78577A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Description
This is a MMP8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CLG 1, CLG1, Collagenase 1, Collagenase 1 neutrophil, HNC, Matrix metallopeptidase 8 (neutrophil collagenase), Matrix metalloprotease 8, Matrix metalloproteinase-8, MMP 8, MMP-8, Mmp8, MMP8, Neutrophil collagenase, PMNL CL, PMNL collagenase, PMNL-CL, PMNLCL
Swiss Prot
P22894
Accession Number
NP_002415
Reactivity
Human
Immunogen
Synthetic peptide of human MMP8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Host or Source
Rabbit
Isotype
IgG

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