ALKBH2 Polyclonal Antibody

• Background :

  The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro) . Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

• Description :

  This is a ALKBH2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  2OG Fe (II) oxy DC1,9530023G02, ABH 2, ABH2, alkB alkylation repair homolog 2, ALKB2, ALKBH2 alkB, ALKBH2, Alkylated DNA repair protein alkB homolog, Alkylated DNA repair protein alkB homolog 2, Alkylation repair homolog 2, Alpha ketoglutarate dependent dioxygenase

• Swiss Prot :

  Q6NS38

• Accession Number :

  BC070489

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant protein of human ALKBH2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.3 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  29 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG