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ALKBH8 Polyclonal Antibody

CAT: 0866-RD252350A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD252350A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
Description
This is a ALKBH8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
4930562C03Rik,8030431D03Rik,9430088N01Rik, ABH8, alkB alkylation repair homolog 8 (E. coli), alkB alkylation repair homolog 8, AlkB homologue 8, ALKB8, ALKBH8, Alkylated DNA repair protein alkB homolog 8, FLJ38204, MGC10235, OTTHUMP00000211286, OTTHUMP00000211287, Pr
Swiss Prot
Q96BT7
Accession Number
BC015183
Reactivity
Human
Immunogen
Full length fusion protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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