Products for Research Use Only

ALKBH1 Polyclonal Antibody

CAT: 0866-RD75414A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD75414A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
Description
This is a ALKBH1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ABH, ABH1, alkB, alkB homolog 1 histone H2A dioxygenase, AlkB, alkylation repair homolog 1 (E. coli), ALKB1, ALKBH, ALKBH1, Alkylated DNA repair protein alkB homolog 1, Alkylation repair homolog 1, Alkylation repair, alkB homolog, Alpha-ketoglutarate-dependent dioxyge
Swiss Prot
Q13686
Accession Number
BC025787
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human ALKBH1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa
Host or Source
Rabbit
Isotype
IgG