ARRB1 Polyclonal Antibody

• Background :

  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

• Description :

  This is a ARRB1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ARB1, ARR1, ARRB1, ARRB1, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1

• Swiss Prot :

  P49407

• Accession Number :

  BC003636

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human ARRB1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.4 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG