ARRB2 Polyclonal Antibody

• Background :

  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a ARRB2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ARRB2, ARB2, ARR2, BARR2

• Gene ID :

  409

• Swiss Prot :

  P32121

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human ARRB2 (NP_004304.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  44 kDa/45 kDa/46 kDa/47 kDa/48 kDa

• Observed Molecular Weight :

  52 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG