ARRB2 Polyclonal Antibody

• Background:

  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a ARRB2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ARRB2, ARB2, ARR2, BARR2

• Gene ID:

  409

• Swiss Prot:

  P32121

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human ARRB2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  46kDa

• Observed Molecular Weight:

  46kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG