ARRB2 Polyclonal Antibody

CAT: 0866-RD88671A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88671A-01Size:60 μL
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Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a ARRB2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ARRB2, ARB2, ARR2, BARR2
Gene ID
409
Swiss Prot
P32121
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ARRB2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Observed Molecular Weight
46kDa
Host or Source
Rabbit
Isotype
IgG

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