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APLP2 Polyclonal Antibody

CAT: 0866-RD267662A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267662A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a APLP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APLP2, APLP-2, APPH, APPL2, CDEBP
Gene ID
334
Swiss Prot
Q06481
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human APLP2 (NP_001135750.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa
Observed Molecular Weight
87 kDa
Host or Source
Rabbit
Isotype
IgG

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