APLP2 Polyclonal Antibody

• Background :

  This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

• Description :

  This is a APLP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  APLP2, APLP-2, APPH, APPL2, CDEBP

• Gene ID :

  334

• Swiss Prot :

  Q06481

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human APLP2 (NP_001135750.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa

• Observed Molecular Weight :

  87 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG