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MSH6 Polyclonal Antibody

CAT: 0866-RD266788A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266788A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Description
This is a MSH6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160
Gene ID
2956
Swiss Prot
P52701
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MSH6 (NP_000170.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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