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MSH4 Polyclonal Antibody

CAT: 0866-RD266200A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266200A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.
Description
This is a MSH4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MSH4
Gene ID
4438
Swiss Prot
O15457
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human MSH4 (NP_002431.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
104 kDa
Observed Molecular Weight
105 kDa
Host or Source
Rabbit
Isotype
IgG

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