MSH4 Polyclonal Antibody

• Background:

  This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

• Description:

  This is a MSH4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MSH4

• Gene ID:

  4438

• Swiss Prot:

  O15457

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein of human MSH4 (NP_002431.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  104 kDa

• Observed Molecular Weight:

  105 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG