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UNC13B Polyclonal Antibody

CAT: 0866-RD266572A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266572A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Description
This is a UNC13B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
UNC13B, MUNC13, UNC13, Unc13h2
Gene ID
10497
Swiss Prot
O14795
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human UNC13B (NP_006368.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
180 kDa/182 kDa
Observed Molecular Weight
210 kDa
Host or Source
Rabbit
Isotype
IgG

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