UNC13D Polyclonal Antibody

• Background:

  This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

• Description:

  This is a UNC13D Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  UNC13D, FHL3, HLH3, HPLH3, Munc13-4

• Gene ID:

  201294

• Swiss Prot:

  Q70J99

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human UNC13D (NP_954712.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  41 kDa/123 kDa/128 kDa

• Observed Molecular Weight:

  123 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG