UNC13D Polyclonal Antibody

• Background :

  This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

• Description :

  This is a UNC13D Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  UNC13D, FHL3, HLH3, HPLH3, Munc13-4

• Gene ID :

  201294

• Swiss Prot :

  Q70J99

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human UNC13D (NP_954712.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:1000-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  41 kDa/123 kDa/128 kDa

• Observed Molecular Weight :

  123 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG