UNC45B Polyclonal Antibody

• Background :

  This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

• Description :

  This is a UNC45B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Cardiomyopathy associated 4 , CMYA4 , FLJ38610, MGC119540, MGC119541, OTTHUMP00000163855, Protein unc 45 homolog B, Protein unc-45 homolog B, SMUNC45, Striated muscle UNC45, UN45B, Unc 45 homolog B (C. elegans), Unc 45 homolog B, UNC 45B, UNC-45B, UNC45 , UNC45B

• Swiss Prot :

  Q8IWX7

• Accession Number :

  BC101063

• Reactivity :

  Human, Mouse

• Immunogen :

  Fusion protein of human UNC45B

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.8 mg/mL

• Dilution :

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  104/95 kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG