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TPMT Polyclonal Antibody

CAT: 0866-RD266207A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266207A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
Description
This is a TPMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TPMT, TPMTD
Gene ID
7172
Swiss Prot
P51580
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TPMT (NP_000358.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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