HLA-DPB1 Polyclonal Antibody

• Background:

  HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

• Description:

  This is a HLA-DPB1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DPB1, HLA-DP, HLA-DP1B, HLA-DPB, HLA-DPB1, major histocompatibility complex, class II, DP beta 1

• Gene ID:

  3115

• Swiss Prot:

  P04440

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human HLA-DPB1 (NP_002112.3) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG