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VGLL1 Polyclonal Antibody

CAT: 0866-RD253198A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253198A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
Description
This is a VGLL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Protein TONDU, TDU, TONDU, Transcription cofactor vestigial like protein 1, Transcription cofactor vestigial-like protein 1, Vestigial like 1, vestigial like 1 homolog (Drosophila), Vgl-1, VGL1, Vgll1, VGLL1
Swiss Prot
Q99990
Accession Number
NP057351
Reactivity
Human
Immunogen
Synthetic peptide of human VGLL1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
WB 1:2000-1:10000 ELISA 1:2000-1:20000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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