Products for Research Use Only

NDI-Lyso

CAT: 0013-GTR19070390-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19070390-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NDI-Lyso is a cathepsin B-activated prodrug that selectively targets cancer cell lysosomes. Upon enzyme-triggered self-assembly into nanofibers, it induces lysosomal membrane permeabilization and caspase-independent cell death, demonstrating potent activity against diverse cancer lines, including drug-resistant models, with low toxicity to normal cells. Its mechanism supports research in lysosome-targeted therapies and non-apoptotic cell death pathways.
Field of Research
Cell Biology, Protein Biochemistry
Molecular Weight
1469.69
Storage Conditions
-20°C
Notes
For research use only.