TMBIM6 antagonist-1

• UNSPSC Description:

  TMBIM6 antagonist-1, a potential TMBIM6 antagonist, prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, and also regulates TMBIM6-leaky Ca2+[1].

• Target Antigen:

  mTOR

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tmbim6-antagonist-1.html

• Smiles:

  O=C(C1=CC=CC=C1N)/C=C/C2=CC=CC([N+]([O-])=O)=C2

• Molecular Weight:

  268.27

• References & Citations:

  [1]Hyun-Kyoung Kim, et al. TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation. Nat Commun. 2020 Aug 11;11(1):4012.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  123134-61-2