Anti-EIF2A Antibody

• Background :

  Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

• Description :

  Boster Bio Anti-EIF2A Antibody (Catalog # M04387-2) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

• Synonyms :

  Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A

• Gene Name :

  EIF2S1

• UniProt :

  P05198

• Host :

  Mouse

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.

• Clonality :

  Monoclonal

• Clone :

  Clone: 1763CT102.71.17

• Applications :

  WB

• Field of Research :

  Apoptosis

• Purification :

  This antibody is purified through a protein G column, followed by dialysis against PBS.

• Dilution :

  WB: 1:2000

• Function :

  162897051628970516289705162897051913133633384352

• Molecular Weight :

  36112 Da

• Shipping Conditions :

  Available

• Storage Conditions :

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment :

  IgG2b, k

• Subcellular Location :

  Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q6ZWX6}. Note=Colocalizes with NANOS3 in the stress granules. {ECO:0000250|UniProtKB:Q6ZWX6}