L-Phenylalanine-d1

L-Phenylalanine-d1

• CAS Number: 54793-54-3
• UNSPSC Description: L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
• Target Antigen: Calcium Channel; Endogenous Metabolite; iGluR; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: OC([C@@H](N)CC1=C([2H])C=CC=C1)=O
• Molecular Weight: 166.20
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported