Human Complement C1R ELISA Kit PicoKine®, Carrier-free

• Background:

  Complement C1r subcomponent is a protein involved in the complement system of the innate immune system. It is mapped to 12p13.31. In humans, C1r is encoded by the C1R gene. C1r along with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active form, by proteolytic cleavage.C1r has been shown to interact with C1s. C1r cleaves C1s to form the active form of C1s.

• :

  heparin, EDTA or citrate

• Description:

  Human Complement C1R ELISA Kit PicoKine® (96 Tests). Quantitate Human C1R in cell culture supernatants, serum and plasma (heparin, EDTA, citrate) and urine. Sensitivity: 0.1ng/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	2705	2824	2677	2767	2743	56.86	2.0%
  Sample 2	11224	12397	11914	11121	11664	521.59	4.4%
  Sample 3	42475	48901	43488	50585	46362	3451.40	7.4%

  *number of samples for each test n=16.

• Synonyms:

  Complement C1r subcomponent; Complement component 1 subcomponent r; C1R

• Gene Name:

  complement C1r

• Gene ID:

  715

• UniProt:

  P00736

• Reactivity:

  Human

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: S18-D705

• Applications:

  ELISA

• Standard:

  100 ng/tube

• Sample Type:

  cell culture supernatants, serum and plasma (heparin, EDTA, citrate) and urine.

• Detection Range:

  1.56 ng/ml - 100 ng/ml

• Sensitivity:

  <0.1 ng/ml

• Function:

  C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.

• Components:

  Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

• Storage Conditions:

  Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Specificity:

  Natural and recombinant human C1R

• Subcellular Location:

  Secreted