Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Carrier-free

• Description:

  Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody catalog # M01577-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDH2;CDHN, NCAD;

• Gene Name:

  Cadherin-2

• UniProt:

  P19022

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthesized peptide derived from human N Cadherin

• Clonality:

  Monoclonal

• Clone:

  Clone: FI-3

• Tissue Specificity:

  Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .

• Applications:

  WB,IHC

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). .

• Components:

  Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

• Storage Conditions:

  Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  99809 MW

• Observed Molecular Weight:

  140 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein.

• Protein Name:

  Lysosome-associated membrane glycoprotein 2 (Lamp2)