Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody catalog # M01577-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN, NCAD

• Gene Name:

  Cadherin-2

• UniProt:

  P19022

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human N Cadherin

• Clonality:

  Monoclonal

• Clone:

  Clone: FI-3

• Tissue Specificity:

  Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .

• Applications:

  WB, IHC

• Field of Research:

  Cadherins, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) . .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200

• Other Gene Names:

  CDH2

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein.

• Protein Name:

  Lysosome-associated membrane glycoprotein 2 (Lamp2)