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Ethacridine (lactate)

CAT: 0804-HY-B2174-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2174-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ethacridine lactate (Acrinol) is a widely used antiseptic and abortifacient. Ethacridine lactate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate is also a poly (ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3].
CAS Number
1837-57-6
Product Name Alternative
Acrinol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Ethacridine_lactate.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
Smiles
CC(O)C(O)=O.NC1=CC2=NC3=CC=C(OCC)C=C3C(N)=C2C=C1
Molecular Formula
C18H21N3O4
Molecular Weight
343.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Rotin LE, et al. Erlotinib synergizes with the poly (ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells. Haematologica. 2016 Nov;101 (11) :e449-e453.|[2]Gupta S, et al. Ethacridine lactate -- a safe and effective drug for termination of pregnancy. Indian J Matern Child Health. 1993;4 (2) :59-61.|[3]Usuki R, et, al. Antibacterial Activity of Acrinol against Organisms Isolated from Clinical Materials and Influence of Light on Antibacterial Activity of Acrinol. Japanese Journal of Pharmaceutical Health Care and Sciences. 2004 Jan; 30 (2) :72-77.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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