Ethacridine

• Description :

  Ethacridine is a poly (ADP-ribose) glycohydrolase (PARG) inhibitor and an activator of the transcriptional coactivator. Ethacridine induces thyroid cancer cells apoptosis and promotes differentiation in thyroid follicular cells[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  Apoptosis; Poly (ADP-ribose) Glycohydrolase (PARG)

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ethacridine.html

• Purity :

  90.0

• Smiles :

  CCOC1=CC2=C(C3=CC=C(C=C3N=C2C=C1)N)N

• Molecular Formula :

  C15H15N3O

• Molecular Weight :

  253.30

• Precautions :

  H302

• References & Citations :

  [1]Huang TS, et al. Ethacridine Induces Apoptosis and Differentiation in Thyroid Cancer Cells In Vitro. Anticancer Res. 2019 Aug;39 (8) :4095-4100.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [442-16-0]